Psychedelic-Assisted Therapy in Europe

What if the thing
you've been looking for
isn't more therapy?

A growing body of clinical research — from Imperial College London to Johns Hopkins — is reshaping what we know about healing depression, trauma, and burnout. We offer a structured, trauma-informed retreat that puts that science into practice.

Psychedelic mushrooms in forest — Vine of the Soul Retreats
Who comes to us

You don't have to be in crisis.

Most of our guests are high-functioning people who have tried the conventional routes. Something is still off — and they know it.

🌑

Mood & Meaning

  • Low mood or persistent flatness
  • Loss of joy in things that used to matter
  • Mid-life questions of purpose
  • Grief or major life transitions

Stress, Anxiety & Burnout

  • Chronic overwhelm or "always on"
  • Performance or social anxiety
  • Unrecognised burnout & depletion
  • Rumination and mental loops
🌿

Sleep & Self-Regulation

  • Insomnia or disrupted rhythms
  • Emotional reactivity or shutdown
  • Desire for steadier calm & focus
  • Feeling disconnected from your body
What is this, exactly?

Psychedelic-assisted
therapy explained

Psychedelic-assisted therapy combines carefully structured psychedelic experiences with professional psychological support — before, during, and after the experience. It is not a ceremony you attend and go home from. It is a therapeutic process in which the psychedelic acts as a catalyst, not a cure.

The medicines used — most commonly psilocybin (found in mushrooms), ayahuasca, and MDMA — work by temporarily quieting the brain's default mode network: the part responsible for the rigid self-narrative that maintains depression, anxiety, and trauma patterns. This creates a window of neuroplasticity — an unusual openness in which deeply held beliefs and emotional patterns can shift.

The key word is structure. Without careful preparation and integration, that window closes without leaving lasting change. With it, the research is striking.

Hand offering mushrooms — psychedelic-assisted therapy at Vine of the Soul Retreats
The science

What the research
actually shows

Over 1,000 peer-reviewed studies on psychedelic-assisted therapy have been published in the last decade. Major universities — Johns Hopkins, Imperial College London, NYU — have dedicated research centres. The findings are consistent enough that Australia legalised psilocybin therapy in 2023, and several European countries are following with regulated frameworks.

This is not fringe science. It is one of the most promising developments in mental health treatment in a generation.

71%
of participants in a Johns Hopkins psilocybin study showed clinically significant reductions in depression symptoms after just two sessions — with effects lasting over 12 months.
Davis et al., JAMA Psychiatry 2021 · Gukasyan et al., J Psychopharmacology 2022
67%
of treatment-resistant PTSD patients no longer met diagnostic criteria after MDMA-assisted therapy in Phase 3 trials, versus 32% in the therapy-only control group.
Mitchell et al., Nature Medicine 2021
6mo
Psilocybin therapy maintained antidepressant effects comparable to a leading SSRI at 6-month follow-up in a head-to-head randomised controlled trial.
Erritzoe et al., EClinicalMedicine / The Lancet 2024
800+
People supported through our structured retreat programmes since 2021, with a 4.7-star Trustpilot rating across 78 verified reviews from past guests.
Vine of the Soul Retreats · Trustpilot verified

"We now have clear evidence that carefully supported psychedelic experiences can produce rapid, substantial, and durable improvements in mental health — for people who haven't responded to conventional treatment."

Imperial College London
Centre for Psychedelic Research
Why this exists

I built this
because I needed it.

In my late thirties, my life looked like success from the outside: career, stability, a relationship, two children. Inside, I was slowly drowning. The world had become something I observed rather than experienced.

I spent years trying to heal — therapy, hypnotherapy, neurofeedback, retreats. Some things helped briefly. Nothing held. The question nobody asked me — the one that would have changed everything — was simple: "Is your body actually capable of integrating anything right now?"

"Depression wasn't an emotion. It was an atmosphere — a weight that wrapped around everything, like moving through honey. I could look at my children and know, intellectually, that I loved them — but the feeling didn't reach my body."

The Retreat

The 5-Day
Flexible Retreat

Our flagship programme. Small groups — maximum 8 people — held in the Algarve, Portugal (sometimes Spain and the Netherlands). You choose which medicines feel right for you: ayahuasca, psilocybin, San Pedro, or non-medicine work. Everything by consent. Real individual care throughout.

This is not a ceremony with a check-in and check-out. It is a structured therapeutic container — with preparation before, integration woven through every day, and professional follow-up after you leave.

See Full Details →
01
Before — 2 weeks

Prepare

Medical screening, dietary preparation, and intention-setting calls. We assess whether you're ready — not just willing. Sometimes we say not yet. That honesty is part of the care.

02
During — 5 days

The Retreat

Daily ceremonies, sharing circles, one-to-one sessions, and integration woven through every day — not bolted on at the end. Held by a team of four trauma-informed, multilingual facilitators.

03
After — ongoing

Integrate

Integration calls, our AI-supported app, and a community that doesn't disappear when you go home. This is where most people either gain ground — or lose what they found. We stay.

For those who want a deeper journey: the full BioPsyche Renewal Protocol wraps everything in a longer therapeutic arc — biological stabilisation first, the retreat, then embodiment support - a six months arc.

Learn about BPR →
Our own data

What our guests
report — 1 year later.

Most retreat operators don't collect outcome data. We do. Most studies only collect short term data. We care about long term ourcomes. In 2025 we surveyed 47 past guests who attended at least 12 months prior — asking them to reflect on lasting change, not just how they felt leaving the retreat. The results are independently collected and unedited.

n=47 · surveyed 12–48 months post-retreat · all responses voluntary and anonymous

0
Guests who reported negative impact or no impact — out of 47 surveyed, more than a year after their retreat.
100% of respondents reported at least some positive impact. This is the number we are most proud of.

"How has the medicine impacted your life so far?"

Life-changing positive impact48.9%
Moderate positive impact27.7%
Slightly positive impact23.4%
No impact0%
Negative impact0%

76.6% reported moderate or life-changing positive impact — more than a year after their retreat.

"Since the retreat, how much clarity or positive change have you noticed in your daily life?"

A great deal27.7%
Quite a lot29.8%
Some27.7%
A little14.9%
None0%

57.5% noticed quite a lot or a great deal of clarity and positive change in daily life at 1-year follow-up.

What people say

800 people.
One consistent truth.

★★★★★

"Those days were the toughest, most profoundly healing, darkest, and yet most luminous and victorious experience of my life so far. I always felt embraced, understood, and gently guided. Their love, patience, devotion and honesty are present in every corner."

— Trustpilot · Algarve retreat

★★★★★

"I arrived very lost, with little to my name, and spent the last of my savings. It turned out to be one of the most important decisions of my life. During those ceremonies, I reconnected with my inner child and became his parent."

— Trustpilot · Returning guest

★★★★★

"I arrived apprehensive. The whole team made me feel welcomed and loved. It's the integration sessions and sharing circles — truly being heard by others on the same journey — that stayed with me most."

— Trustpilot · September 2024

★★★★★

"Bianca — her professionalism, integrity and support before, throughout and after — is above all a lovely human being full of acceptance and understanding. You feel relaxed like you are around family from the very first moment."

— Trustpilot · Verified guest

Hear it directly

Your questions,
answered.

In this Q&A, Bianca addresses the questions she hears most often — from people who are curious but cautious, who have done their research but still aren't sure.

If you have a question that isn't covered, the discovery call is the right place to bring it. No question is too basic. No concern is too small.

Book a Call →
The first step

A conversation
worth having.

The discovery call is not a sales call. It is a structured 45-minute conversation in which we map where you are, what has and hasn't worked, and whether any of what we offer makes sense for you right now.

You will leave with a clearer picture of your own patterns — regardless of whether you ever book a retreat. Many people tell us the call alone shifted something. That is by design.

If you go on to join a retreat, the call fee is fully deducted from the retreat price.

Discovery Call

What you get

  • A structured 45-minute 1:1 conversation with Bianca
  • Clarity on your specific situation — what's keeping you stuck and why
  • An honest assessment of whether retreat work is right for you right now
  • A personal recommendation — even if that recommendation is something else entirely
  • A framework you can use immediately, whatever you decide
✓ The €40 call fee is fully deducted from your retreat price if you book.
€40

45-60 minutes · Fully deductible · No obligation

Book Your Discovery Call