What if the thing
you've been looking for
isn't more therapy?
A growing body of clinical research — from Imperial College London to Johns Hopkins — is reshaping what we know about healing depression, trauma, and burnout. We offer a structured, trauma-informed retreat that puts that science into practice.
You don't have to be in crisis.
Most of our guests are high-functioning people who have tried the conventional routes. Something is still off — and they know it.
Mood & Meaning
- Low mood or persistent flatness
- Loss of joy in things that used to matter
- Mid-life questions of purpose
- Grief or major life transitions
Stress, Anxiety & Burnout
- Chronic overwhelm or "always on"
- Performance or social anxiety
- Unrecognised burnout & depletion
- Rumination and mental loops
Sleep & Self-Regulation
- Insomnia or disrupted rhythms
- Emotional reactivity or shutdown
- Desire for steadier calm & focus
- Feeling disconnected from your body
Psychedelic-assisted
therapy explained
Psychedelic-assisted therapy combines carefully structured psychedelic experiences with professional psychological support — before, during, and after the experience. It is not a ceremony you attend and go home from. It is a therapeutic process in which the psychedelic acts as a catalyst, not a cure.
The medicines used — most commonly psilocybin (found in mushrooms), ayahuasca, and MDMA — work by temporarily quieting the brain's default mode network: the part responsible for the rigid self-narrative that maintains depression, anxiety, and trauma patterns. This creates a window of neuroplasticity — an unusual openness in which deeply held beliefs and emotional patterns can shift.
The key word is structure. Without careful preparation and integration, that window closes without leaving lasting change. With it, the research is striking.
What the research
actually shows
Over 1,000 peer-reviewed studies on psychedelic-assisted therapy have been published in the last decade. Major universities — Johns Hopkins, Imperial College London, NYU — have dedicated research centres. The findings are consistent enough that Australia legalised psilocybin therapy in 2023, and several European countries are following with regulated frameworks.
This is not fringe science. It is one of the most promising developments in mental health treatment in a generation.
"We now have clear evidence that carefully supported psychedelic experiences can produce rapid, substantial, and durable improvements in mental health — for people who haven't responded to conventional treatment."
Imperial College LondonCentre for Psychedelic Research
Bianca · Founder & Lead Facilitator
I built this
because I needed it.
In my late thirties, my life looked like success from the outside: career, stability, a relationship, two children. Inside, I was slowly drowning. The world had become something I observed rather than experienced.
I spent years trying to heal — therapy, hypnotherapy, neurofeedback, retreats. Some things helped briefly. Nothing held. The question nobody asked me — the one that would have changed everything — was simple: "Is your body actually capable of integrating anything right now?"
"Depression wasn't an emotion. It was an atmosphere — a weight that wrapped around everything, like moving through honey. I could look at my children and know, intellectually, that I loved them — but the feeling didn't reach my body."
I built this because I needed it.
A personal story about desperation, cost, and why structure matters more than the medicine.
There is a memory I return to sometimes, not because it was dramatic, but because it exposed something I couldn’t explain at the time.
We were on holiday in the mountains. A beautiful hotel. A private spa. The kind of place where life feels curated: warm sauna, bubbling whirlpool, sparkling wine, fresh fruit, a view of snow-covered peaks that looks almost fake. My twins were being cared for. My husband was beside me. The world had gone quiet in that luxurious way people pay a lot of money for — the promise of ease.
And I remember lying there thinking: this is the moment I’m supposed to feel happy. But I didn’t. Not even a little.
What I felt instead was a heaviness that didn’t match the scene. A dark cloud, not in the poetic way, but in the clinical way — a dull atmosphere that followed me everywhere, even into places that should have felt like paradise. I wasn’t crying. I wasn’t having a breakdown. I was functioning. I was smiling when I needed to. I was doing life. I just couldn’t feel life.
Because the outside looked so good, I made the only conclusion that seemed logical: I must be ungrateful. I must be broken. I must be a fraud.
That internal voice didn’t come from nowhere. My childhood had trained it into me. I grew up in Romania, in a German-speaking community, in a home where love didn’t feel safe. My mother was depressed. She could be violent. The worst part wasn’t even the hitting — it was the terror of never knowing when the next criticism, the next outburst, the next blow would come. When she died by suicide when I was sixteen, it shattered me, and in a strange way it also felt like a doorway out of a prison. It was freedom, and it was loss, and it imprinted something in me that I would only understand much later: that suffering can become a normal climate, and “functioning” can become a survival strategy.
I did what many driven people do: I built a life that looked like proof I was okay.
I worked hard. I became successful professionally. I moved to Germany because it felt like home in a way Romania never had. I had my twins at 32 and for a while I was a single parent. Anyone who has cared for two babies at once knows that you don’t “get tired.” You live in an altered state of exhaustion. You stop sleeping properly. Your body starts operating on stress hormones. And because I needed to keep everything afloat, I kept pushing.
I worked a demanding job, I freelanced on the side, I moved multiple times with small children, I barely slept for years — three hours, four hours, sometimes less. And when the children finally slept, I couldn’t anymore. Insomnia had become my baseline. My immune system was a mess. I was sick constantly. I didn’t call it burnout because I didn’t even have the concept for it back then. I just called it responsibility. Ambition.
From the outside, it looked like competence. Inside, it looked like panic disguised as productivity.
Then there was a cancer scare. It turned out not to be malignant, but the fear itself cracked something open. It was as if my system finally said: enough. And I slid into depression — not the movie version, but the quieter kind: the one where you keep showing up while slowly disappearing.
At home, things got harder. My marriage suffered. My husband didn’t understand what was happening — partly because I couldn’t explain it myself, and partly because the way conflict sounded in his voice woke up the little traumatised child inside me. In arguments, I wasn’t an adult anymore. I was sixteen. I was nine. I was five. I couldn’t find words. I could only defend myself with emotion, which made things worse. The fights got louder. The children got caught in it. And I watched myself becoming the kind of mother I never wanted to be: impatient, overwhelmed, unavailable, harsh.
One evening, driving home from work, a thought entered my mind that stopped me cold: what if I just don’t turn at the next bend?
That thought terrified me — not only because it was there, but because it arrived with a calm logic that made it feel possible. And then it disappeared for exactly one reason: I knew what my mother left behind. I knew the damage that kind of choice creates in the people who have to live afterward. I could not do that to my sons.
So I stayed. But that created a particular kind of hell: I cannot live, and I will not die.
I started searching for help in the ways people are taught to search: therapy, treatments, techniques, fixes. I went to a therapist; after two sessions he suggested inpatient treatment. For a moment, I felt relief — the idea of three weeks away from everything sounded like oxygen. I came home and told my husband, expecting support. What I got was: “And who will take care of the children?” And then we never spoke about it again. That was a quiet kind of heartbreak. Not because he was a villain — he wasn’t. He was a good man. But in that moment I realised something painful: even inside marriage, you can be alone.
Body therapies ~€4,000 · Retreats ~€6,000 · Tests & supplements ~€1,500
Courses, books, coaches ~€5,800
+ 18 months unable to earn · + career rebuilt from scratch
I took sick leave. I began to meditate. I started learning about depression, trauma, nervous systems. I changed my diet. I began doing the slow, unglamorous work of stabilising myself. I started sleeping again after years of insomnia — and then something happened that still feels surreal when I describe it: after years of depression, it lifted suddenly from one day to the next.
Beauty came back. The ability to sense meaning returned. And along with that came grief: grief for the years I had lost, grief for the damage done, grief for the marriage, grief for the mother I never had, grief for the children’s childhood I had partially missed while I was physically present but internally gone.
Around that time I discovered hypnotherapy and later plant medicine. And I want to be very precise here: psychedelics were not the miracle. They were not a shortcut. They were a catalyst — but only because I had done the stabilisation first.
This is one of the biggest misunderstandings in the public conversation right now. People talk about psychedelic-assisted therapy as if it’s simply taking psychedelics with nicer music. Or they treat it like the new miracle cure. That framing is dangerous. Because insight does not transform you when your system is depleted. You can have the most profound realisation of your life and still wake up two days later living the same pattern, because your nervous system does not have the capacity to hold the change.
The question that could have saved me years was simple: Is your body capable of integrating anything right now?
This is why I built Vine of the Soul Retreats. Not as ceremonies, but as a structured therapeutic container: preparation before, safety during, integration woven through, and follow-up after. Because the medicine is not the map. The map is what helps people keep what they found.
— Bianca, Founder & Lead Facilitator
The 5-Day
Flexible Retreat
Our flagship programme. Small groups — maximum 8 people — held in the Algarve, Portugal (sometimes Spain and the Netherlands). You choose which medicines feel right for you: ayahuasca, psilocybin, San Pedro, or non-medicine work. Everything by consent. Real individual care throughout.
This is not a ceremony with a check-in and check-out. It is a structured therapeutic container — with preparation before, integration woven through every day, and professional follow-up after you leave.
See Full Details →Prepare
Medical screening, dietary preparation, and intention-setting calls. We assess whether you're ready — not just willing. Sometimes we say not yet. That honesty is part of the care.
The Retreat
Daily ceremonies, sharing circles, one-to-one sessions, and integration woven through every day — not bolted on at the end. Held by a team of four trauma-informed, multilingual facilitators.
Integrate
Integration calls, our AI-supported app, and a community that doesn't disappear when you go home. This is where most people either gain ground — or lose what they found. We stay.
For those who want a deeper journey: the full BioPsyche Renewal Protocol wraps everything in a longer therapeutic arc — biological stabilisation first, the retreat, then embodiment support - a six months arc.
Learn about BPR →What our guests
report — 1 year later.
Most retreat operators don't collect outcome data. We do. Most studies only collect short term data. We care about long term ourcomes. In 2025 we surveyed 47 past guests who attended at least 12 months prior — asking them to reflect on lasting change, not just how they felt leaving the retreat. The results are independently collected and unedited.
n=47 · surveyed 12–48 months post-retreat · all responses voluntary and anonymous
"How has the medicine impacted your life so far?"
76.6% reported moderate or life-changing positive impact — more than a year after their retreat.
"Since the retreat, how much clarity or positive change have you noticed in your daily life?"
57.5% noticed quite a lot or a great deal of clarity and positive change in daily life at 1-year follow-up.
800 people.
One consistent truth.
"Those days were the toughest, most profoundly healing, darkest, and yet most luminous and victorious experience of my life so far. I always felt embraced, understood, and gently guided. Their love, patience, devotion and honesty are present in every corner."
— Trustpilot · Algarve retreat
"I arrived very lost, with little to my name, and spent the last of my savings. It turned out to be one of the most important decisions of my life. During those ceremonies, I reconnected with my inner child and became his parent."
— Trustpilot · Returning guest
"I arrived apprehensive. The whole team made me feel welcomed and loved. It's the integration sessions and sharing circles — truly being heard by others on the same journey — that stayed with me most."
— Trustpilot · September 2024
"Bianca — her professionalism, integrity and support before, throughout and after — is above all a lovely human being full of acceptance and understanding. You feel relaxed like you are around family from the very first moment."
— Trustpilot · Verified guest
Your questions,
answered.
In this Q&A, Bianca addresses the questions she hears most often — from people who are curious but cautious, who have done their research but still aren't sure.
If you have a question that isn't covered, the discovery call is the right place to bring it. No question is too basic. No concern is too small.
Book a Call →A conversation
worth having.
The discovery call is not a sales call. It is a structured 45-minute conversation in which we map where you are, what has and hasn't worked, and whether any of what we offer makes sense for you right now.
You will leave with a clearer picture of your own patterns — regardless of whether you ever book a retreat. Many people tell us the call alone shifted something. That is by design.
If you go on to join a retreat, the call fee is fully deducted from the retreat price.
What you get
- A structured 45-minute 1:1 conversation with Bianca
- Clarity on your specific situation — what's keeping you stuck and why
- An honest assessment of whether retreat work is right for you right now
- A personal recommendation — even if that recommendation is something else entirely
- A framework you can use immediately, whatever you decide
45-60 minutes · Fully deductible · No obligation
Book Your Discovery Call